With Jailbreaking and Unlocking there is a strange game of cat and mouse played between the jeailbreakers and Apple. It would appear that this game has also extended to the new Palm Pre.
Palm has released its new Web OS 1.1 and it fixes the issue that Apple just patched with the latest version of iTunes. So that means that you can still sync your Palm Pre with iTunes if you have the newest version of the Web OS.
Other improvements are emoticons and full exchange support, but between you and me the best part is Palm's back hand to Apple and their iron grip on iTunes.