ASRock have opted for the UEFI BIOS which doesn't come as a surprise since they used it on their P67 motherboards. That means you can of course use the mouse, but most will probably find it easier and faster to use the keyboard.
The first screen you're greeted with just gives us a quick rundown of what we're dealing with. As you can see, these pictures were taken when our CPU was overclocked.
The OC Tweaker section gives you really everything to do with overclocking. Unlike the P67 Extreme6, though, DRAM settings have been thrown into a separate menu.
Advanced lets you dive deeper into the configuration of the board. Most won't have a need to go into this area; some may venture into the CPU area, though, to disable some of the tech that can limit overclocking potential.
Scrolling through the rest of the screens doesn't hold any surprises with H/W Monitor, Boot, Security and Exit all being quite self-explanatory.