New vaccines that can spread on their own are being developed

Research is being done in Europe and the United States into lab-modified self-spreading and replicating viral vaccines in animals.

Published Jan 7, 2022 5:30 AM CST   |   Updated Wed, Feb 2 2022 12:02 AM CST
1 minute & 12 seconds read time

A new article published in the Science journal explores how this defies the previous norm.

New vaccines that can spread on their own are being developed 02 | TweakTown.com

In 1974, the first lab-modified virus capable of replicating was produced. Since then, the scientific consensus has been that too many modifications to the virus' genome will make it too unstable to release into an uncontrolled environment safely.

Consequently, lab-modified viral vaccines have been made with their ability to spread from the host individual to others removed or significantly diminished. Successful vaccines include the polio vaccine for humans or rabies vaccines for wild animals.

Scientists in Spain are now conducting a contained experiment involving vaccinating pigs against African swine fever with self-spreading viruses. Additionally, a four-year-long research project based in the U.S. has recently concluded, which mathematically identified deployment strategies for such vaccines. The U.S. Department of Defense's research agency, DARPA, is currently funding experimentation related to lab-modified self-spreading animal vaccines.

"If, as is argued, self-spreading vaccines are potentially transformational in a wide array of agricultural, medical and conservation uses, then developers and funders should commit to address needs within their own borders, rather than continue to propose equatorial nations for field testing," said Guy Reeves of the Max Planck Institute for Evolutionary Biology.

"This will maximize the chances of a robust debate among fellow citizens and nations about the wisdom of self-spreading viral approaches in the environment. In this respect the EU funded project to address a serious pig disease within its own territories could be viewed as a step in this direction," Reeves continued.

You can read more from the article here.

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NEWS SOURCES:phys.org, doi.org

Adam grew up watching his dad play Turok 2 and Age of Empires on a PC in his computer room, and learned a love for video games through him. Adam was always working with computers, which helped build his natural affinity for working with them, leading to him building his own at 14, after taking apart and tinkering with other old computers and tech lying around. Adam has always been very interested in STEM subjects, and is always trying to learn more about the world and the way it works.

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