The Crosshair IV Formula was a very easy board to use. We had no problems getting it set up and running. This same simple setup should translate to others that are running dual and tri core CPUs (even a few with "T" series X4s) as you will have the option to potentially unlock cores on your CPUs with the simple press of a button. The same can be said for simple overclocking with the Turbo Key II button.
The layout of the board seems a little cluttered at first, but overall gives you some good flexibility and also places the components in a way that allows for good heat dissipation across the board. In general the only problems we had were with the Phenom II X6 1090T that we used and the 8-Pin 12V Aux power connector. The rest of the installation and setup were a dream.