Something I don't think I could ever do without half pissing my pants would be to spend twelve months up on the International Space Station (ISS). At the moment, there's an enforced six-month maximum stay on the ISS, but all this changes in 2015.
In 2015, the maximum stay will increase to twelve months, where one Russian and one American will spend an entire year on the ISS. The mission is to help collect more data to help us work out a way of completing deep space travel.
There's already been plenty of data collected, mainly about the effects microgravity has on the human body, but because of the six-month only stays, there's not much information on long-term implications on the human body. Michael Suffredini, International Space Station program manager says:
In order for us to eventually move beyond low Earth orbit, we need to better understand how humans adapt to long-term spaceflight. The space station serves as a vital scientific resource for teaching us those lessons, and this yearlong expedition aboard the complex will help us move closer to those journeys.