To tell you the truth, I didn't know what I was going to do with a 39-inch, 4K display, until days into using it. I did my unboxing video, and then I tried using it as my everyday display, but it is just too damn big. I found myself not using the desktop real estate as much as I wanted, and then I began having issues with the panel.
I was getting a black screen problem, where the monitor would drop signal for a few seconds, and then come back to life, to only drop signal again seconds after. It was unusable at this point, but I found it to be a problem with what I was running: Intel's NUC.
I grabbed another Corsair Neutron GTX SSD, slotted my two NVIDIA GeForce GTX 780s into my test bed setup, and installed Windows from scratch; this is a near daily process around here with what I'm doing in my office. Once it was up and running -yeah baby, that's 4K.
The Seiki Digital SE39UY04 doesn't look too good at all out of the box, so you'll want to change the following settings: