To be as frank as I possibly can, the P43 chipset really doesn't do anything special for us. Intel already has a high-end chipset with the X48 along with full speed CrossfireX support. And the P45 with its split 8/8 design makes a good chipset for the enthusiast and mid-range market. The P43 just seems like another chipset Intel wants to push to make more money.
If this had an IGP or something in it then we would think it worth another name. Put clearly, it's just a cut down P45. The P43 chipset itself isn't that much cheaper than P45, meaning that you're still going to be shelling out close to what a base line P45 board would cost you and P45 will give you true Crossfire support where P43 uses the older and slower 16/4 design, providing the board even has two x16 slots.
GIGABYTE's EP43-DS3R board, however, is extremely well designed for a mid-range board. But the P43 chipset simply doesn't do much for us; you would be better off with a P45 board if you want this board for Crossfire. The EP45-DS3R would be a far better option, especially since they aren't that much different in price.