ASUS has been one of the biggest motherboard producers in history; there are only a few companies with as much of a diverse product portfolio as the ASUS company, and they are the likes of MSI and GIGABYTE who are ASUS' main competitors.
As always, the top line of ASUS boards never fail to impress with their style, functionality, features and ease of use. The P5E3 Premium WiFi really continues this trend with great style. The layout of the board is almost flawless with features we would like to see other companies implement such as the Express Gate Pre-BIOS allowing you to access the Internet, instant messaging, webmail and even YouTube (why you would want that without sound or video acceleration is beyond me, but I guess some of you may still find it useful).
This makes this board totally unique from the others out there, but next time we hope to see ASUS doing away with BIOS' and going for the new (well, not actually new) Extended Firmware Interface that is designed to take BIOS out completely; this would make ASUS' high-end boards even more fantastic.
While very limited in the shops just now, the board is extremely expensive in nature, this being because of the X48 premium that the board comes with. You're going to need deep pockets to afford one of these babies, but if you're after everything this board offers, its definitely a good buy.